“The findings support the growing association between vitamin D and cancer risk and outcomes, and suggest that vitamin D supplements might help even those patients already diagnosed with some forms of cancer.” Matthew Drake, MD, PhD
The quote above I found on an article related to vitamin D deficiency and its relationship to cancer and cancer progression from ProHealth. More & more information is continually being revealed on how dangerous vitamin D deficiency is. According to this recent ProHealth article:
A new study has found that the amount of vitamin D in patients being treated for diffuse large B-cell (non-Hodgkins) lymphoma was strongly associated with cancer progression and overall survival.
“These are some of the strongest findings yet between vitamin D and cancer outcome,” says the study’s lead investigator, Matthew Drake, MD, PhD, an endocrinologist at Mayo Clinic in Rochester. “While these findings are very provocative, they are preliminary and need to be validated in other studies. However, they raise the issue of whether vitamin D supplementation might aid in treatment for this malignancy, and thus should stimulate much more research.”
If you would like to view a You Tube video summary of this video, please click here to watch Mayo Clinic Study Finds Vitamin D Associated with Survival in Lymphoma Patients. The study was conducted by researchers at the Mayo Clinic & the University of Iowa, who participate in SPORE – University of Iowa/Mayo Clinic Lymphoma Specialized Program of Research Excellence – that is funded by the National Cancer Institute.
Out of the 374 study participants who were newly diagnosed with non-Hodgkins lymphoma, 50% were deficient in vitamin D levels based on the commonly used clinical value of total serum 25(OH)D less than 25 ng/mL. This study was not a clinical trial, but an epidemiologic study designed to identify predictors of outcomes in lymphoma. Because this was not a clinical trial, patient management and treatments were not assigned. The standard care for clinical practice was followed in this study.
Patients with deficient vitamin D levels had a 1.5-fold greater risk of disease progression and a twofold greater risk of dying, compared to patients with optimal vitamin D levels after accounting for other patient factors associated with worse outcomes.
The findings of this study support the growing association between vitamin D levels, risk of cancer and outcomes. The findings also suggest that vitamin D supplements might even possibly help the patients currently diagnosed with some forms of cancer, according to Dr. Drake. He also said that:
“The exact roles that vitamin D might play in the initiation or progression of cancer is unknown, but we do know that the vitamin plays a role in regulation of cell growth and death, among other processes important in limiting cancer.”
There have also been studies done that suggest vitamin D deficiency may play a role in causing certain types of cancer and the outcome may also be affected once someone is diagnosed with cancer. Reports have also discovered that vitamin D deficiency is associated with poor outcomes in these cancers: breast, colon, head & neck.