ME/CFS Research Abstracts From ProHealth

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ProHealth.com is on top of all of the latest research news available on ME/CFS.  Here are abstracts from the latest research that you can check out!

Low B12 is major depression risk for women – large population study

An association between low blood levels of folate [vitamin B(9)], vitamins B(6) and B(12) and a higher prevalence of depressive symptoms has been reported in several epidemiological studies.  The present study aimed to assess the association between folate, vitamins B(6) and B(12) intake and depression prevalence in the SUN cohort study [a tracking study of university graduates in Spain focused on identifying dietary determinants of various illnesses and conditions].

Below-normal blood volume typical in ME/CFS patients – Klimas, et al.

This study examined whether deficits in cardiac output and blood volume in a Chronic Fatigue Syndrome (CFS) cohort were present and linked to illness severity and sedentary lifestyle.  Follow-up analyses assessed whether differences between CFS and control groups in cardiac output levels were corrected by controlling for cardiac contractility and total blood volume (TBV).

Distinctive measures of cognitive impairment demonstrated in ME/CFS

This study addresses, among other things, the debate as to whether cognitive deficits do occur with a diagnosis of Chronic Fatigue Syndrome (CFS). Previous studies have indicated a potential mismatch between subjective patient ratings of impairment and clinical assessment.

Backache, headache, leg weakness/tingling may be undiagnosed POTS

Clinicians depend on history given by the patients when considering the diagnosis of orthostatic hypotension. [A condition in which a person’s blood pressure falls significantly when the person stands up, immediately or within a few moments.]

Post-exertion fatigue linked to poor ‘stress-response’ protein production

As heat shock proteins (Hsp) protect the cells against the deleterious effects of oxidative stress, we hypothesized that Hsp expression might be reduced in patients suffering from chronic fatigue syndrome (CFS) who present an accentuated exercise-induced oxidative stress.

Physiological measures identify limited movement pattern in ME/CFS

Chronic fatigue syndrome (CFS) is an illness characterized by pervasive physical and mental fatigue without specific identified pathological changes. Many patients with CFS show reduced physical activity which, though quantifiable, has yielded little information to date. Nonlinear dynamic analysis of physiological data can be used to measure complexity in terms of dissimilarity within timescales and similarity across timescales. A reduction in these objective measures has been associated with disease and aging.

Poor diagnosis of ‘early Lyme-like’ cases points to need for education

Lyme disease, the most common vector-borne infection in North America, is increasingly reported. When the characteristic rash, erythema migrans, is not recognized and treated, delayed manifestations of disseminated infection may occur. The accuracy of diagnosis and treatment of early Lyme disease in the community is unknown.

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